The server that runs this site is located in a datacenter in which there are thousands of other servers running at the same time 24/7 non stop. As long as your computer is kept cool and well ventilated, it can run 24/7 without an issue. Oh but make sure you turn monitors off if you're not using them or have a good screen saver up, monitors if left on for long periods of time without a screen saver can burn out. I've seen several go.
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